Dimethyl fumarate ameliorated pyroptosis in contrast-induced acute renal injury by regulating endoplasmic reticulum stress and JAK2-STAT3 pathway
This study demonstrated that DMF had renoprotective effects on CIAKI. DMF ameliorated pyroptosis through the inhibition of ERS and the JAK2-STAT3 pathway.
Authors
- Youhua Xu (ORCID: https://orcid.org/0000-0002-3258-013X)
- Min Yin (ORCID: https://orcid.org/0000-0002-6297-0016)
- Xieyi Guo
- Dongsheng Cheng (ORCID: https://orcid.org/0000-0003-1593-8950)
- Dingkun Gui (ORCID: https://orcid.org/0000-0003-3168-4778)
- Yilan Shen
- Xiaoning An
Institutions
- Macau University of Science and Technology (MO)
- Shanghai Jiao Tong University (CN)
- Quality Research (US)
- Shanghai Sixth People's Hospital (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1080/0886022x.2025.2504633
- Citations
- 10
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 14.31
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China