Apurinic/apyrimidinic endonuclease 1/redox factor-1 deficiency exacerbates renal fibrosis in a unilateral ureteral obstruction model
APE1/Ref-1 deficiency exacerbates fibrosis, macrophage infiltration, and apoptosis. APE1/Ref-1 also modulates EMT in vitro, highlighting its protective function in chronic kidney disease.
Authors
- Cuk‐Seong Kim (ORCID: https://orcid.org/0000-0001-7647-6089)
- Dae Eun Choi (ORCID: https://orcid.org/0000-0003-2870-3958)
- Byeong Hwa Jeon (ORCID: https://orcid.org/0000-0002-3347-2739)
- Hee Kyoung Joo
- Eun-Ok Lee
- Sung‐Min Kim (ORCID: https://orcid.org/0000-0003-3156-7133)
- Eun Ju Choi (ORCID: https://orcid.org/0000-0001-6629-2876)
- Hao Jin (ORCID: https://orcid.org/0009-0005-6855-6667)
- Yu Ran Lee
Institutions
- Chungnam National University (KR)
- Chungnam National University Hospital (KR)
Publication Details
- Journal
- Kidney Research and Clinical Practice
- Published
- 2025-05-19
- DOI
- https://doi.org/10.23876/j.krcp.24.281
- Citations
- 1
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Chungnam National University