From a nonlinear kinetic equation to a volume-exclusion chemotaxis model via asymptotic preserving methods
In this work we first prove, by formal arguments, that the diffusion limit of nonlinear kinetic equations, where both the transport term and the turning operator are density-dependent, leads to volume-exclusion chemotactic equations. We then numerically study this diffusive limit via an asymptotic preserving scheme based on a micro-macro decomposition. By properly discretizing the nonlinear term implicitly-explicitly in an upwind manner, the scheme produces accurate approximations also in the case of strong chemosensitivity. We show, via detailed calculations, that the scheme is asymptotic preserving and bound preserving and show numerically an energy dissipation property, which are essential for practical applications. We extend this scheme to two dimensional kinetic models and we validate its efficiency by means of 1D and 2D numerical experiments of pattern formation in biological systems.
Authors
- Gissell Estrada-Rodriguez (ORCID: https://orcid.org/0000-0001-6202-9384)
- Xinran Ruan (ORCID: https://orcid.org/0000-0002-2094-1292)
- Diane Peurichard (ORCID: https://orcid.org/0000-0002-0807-2266)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Laboratoire Jacques-Louis Lions (FR)
- Capital Normal University (CN)
Publication Details
- Journal
- Kinetic and Related Models
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3934/krm.2025012
- Primary Topic
- Mathematical Biology Tumor Growth
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- National Natural Science Foundation of China
- Fondation Sciences Mathématiques de Paris