From a nonlinear kinetic equation to a volume-exclusion chemotaxis model via asymptotic preserving methods

In this work we first prove, by formal arguments, that the diffusion limit of nonlinear kinetic equations, where both the transport term and the turning operator are density-dependent, leads to volume-exclusion chemotactic equations. We then numerically study this diffusive limit via an asymptotic preserving scheme based on a micro-macro decomposition. By properly discretizing the nonlinear term implicitly-explicitly in an upwind manner, the scheme produces accurate approximations also in the case of strong chemosensitivity. We show, via detailed calculations, that the scheme is asymptotic preserving and bound preserving and show numerically an energy dissipation property, which are essential for practical applications. We extend this scheme to two dimensional kinetic models and we validate its efficiency by means of 1D and 2D numerical experiments of pattern formation in biological systems.

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Publication Details

Journal
Kinetic and Related Models
Published
2025-01-01
DOI
https://doi.org/10.3934/krm.2025012
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

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article

From a nonlinear kinetic equation to a volume-exclusion chemotaxis model via asymptotic preserving methods

Gissell Estrada-Rodriguez, Xinran Ruan, Diane Peurichard
Kinetic and Related Models
Mathematical Biology Tumor Growth
article

From a nonlinear kinetic equation to a volume-exclusion chemotaxis model via asymptotic preserving methods

Gissell Estrada-Rodriguez, Xinran Ruan, Diane Peurichard
article en

Abstract

In this work we first prove, by formal arguments, that the diffusion limit of nonlinear kinetic equations, where both the transport term and the turning operator are density-dependent, leads to volume-exclusion chemotactic equations. We then numerically study this diffusive limit via an asymptotic preserving scheme based on a micro-macro decomposition. By properly discretizing the nonlinear term implicitly-explicitly in an upwind manner, the scheme produces accurate approximations also in the case of strong chemosensitivity. We show, via detailed calculations, that the scheme is asymptotic preserving and bound preserving and show numerically an energy dissipation property, which are essential for practical applications. We extend this scheme to two dimensional kinetic models and we validate its efficiency by means of 1D and 2D numerical experiments of pattern formation in biological systems.

Kinetic and Related ModelsVol. 18(6)
Centre National de la Recherche Scientifique (FR), Université Paris Cité (FR), Sorbonne Université (FR), Laboratoire Jacques-Louis Lions (FR), Capital Normal University (CN)
Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, National Natural Science Foundation of China, Fondation Sciences Mathématiques de Paris
Reduced inequalities
Openalex Percentile: Top 87%
Mathematical Biology Tumor Growth
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