Evaluation of the antibacterial activity of polyalkenate cement modified with metal-containing nanoparticles

Aim – assessment of the level of antibacterial effect of polyalkenate (glass ionomer) cement modified with nanoparticles of vanadium oxide (V2O5), aluminum oxide (Al2O3) and magnetite (Fe3O4) in relation to a test culture of Staphylococcus aureus and a mixed microbiota of saliva. Material and methods. Colloidal aqueous solutions of metals and their oxides with a stabilizer were obtained using the electroerosion method. The polyalkenate cement “Cemion” was saturated with colloidal solutions during mixing. The antimicrobial activity of the modified filling material was evaluated in relation to the mixed microbiota (saliva) and the test culture of S. aureus by the in vitro disco diffusion method. Results. The exposure time of the seals was 24 hours at 37 °C in the thermostat. As a result, samples 1-5 showed no areas of delayed microbial growth. Sample 6 showed a growth retardation zone: 19 mm on a cup with S. aureus and 15 mm on a cup with mixed microbiota. Conclusion. Polyalkenate cement modified with a colloidal aqueous solution of magnetite can be effective in preventing recurrent dental caries.