Natural and long-term preservable anticoagulant property of SiO2 and TiO2 bilayer films
By maintaining a hydrophilic, clean surface with abundant surface -OH groups, the SiO<sub>2</sub>/TiO<sub>2</sub> bilayer achieved superior intrinsic anticoagulant performance that was preserved over long-term storage. This bilayer approach addresses key limitations of TiO<sub>2</sub>, suggesting that SiO<sub>2</sub>/TiO<sub>2</sub> coatings are a promising alternative to pure TiO<sub>2</sub> films for blood-contacting devices.
Authors
- Nan Huang (ORCID: https://orcid.org/0000-0003-0871-158X)
- H. Jiang (ORCID: https://orcid.org/0000-0002-4325-2270)
- Zikun He
- Qiongjian Huang
- Ansha Zhao (ORCID: https://orcid.org/0000-0002-1588-7594)
- Xiang‐Qin Liu
- Xiao Chen (ORCID: https://orcid.org/0000-0002-4269-9089)
- Jiang Chen (ORCID: https://orcid.org/0000-0002-6842-8471)
- Hong Sun
- Ping Yang (ORCID: https://orcid.org/0009-0007-7144-189X)
Institutions
- University of Electronic Science and Technology of China (CN)
- Longgang Central Hospital (CN)
- Zhejiang Industry Polytechnic College (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- Southwest Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fbioe.2025.1578099
- Primary Topic
- Polymer Surface Interaction Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China