Analysis of the correlation between RFC4 expression and tumor immune microenvironment and prognosis in patients with cervical cancer
RFC4 is highly expressed in CC tissues. However, patients with high RFC4 expression in CC have a better prognosis, possibly because RFC4 exerts antitumor effects by affecting the immunostimulatory tumor microenvironment, such as immunostimulatory and dendritic cell infiltration.
Authors
- Bifen Huang
- Jian-Qing Zheng (ORCID: https://orcid.org/0000-0002-1823-1419)
- Bizhen Chen (ORCID: https://orcid.org/0009-0000-8559-9996)
- Li-hua Xiao (ORCID: https://orcid.org/0009-0008-3601-9201)
- Min Wu (ORCID: https://orcid.org/0000-0002-9666-7138)
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fgene.2025.1514383
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87