Latent tuberculosis coinfection in mild COVID-19 is associated with a distinct immune cell phenotype marked by enhanced cytotoxic degranulation and mitochondrial alterations
The findings reveal significant alterations in monocytes and T cells of individuals with LTBI/COVID-19, suggesting that co-infection may induce changes in the cellular phenotype and cytotoxic function of CD8 T cells.
Authors
- Lucero A. Ramón‐Luing (ORCID: https://orcid.org/0000-0003-2004-7570)
- M. Martinez-Moreno
- Norma A. Téllez-Navarrete (ORCID: https://orcid.org/0000-0002-2886-8317)
- Eduardo Becerril‐Vargas (ORCID: https://orcid.org/0000-0003-1339-3942)
- Marco Antonio Vargas-Hernández (ORCID: https://orcid.org/0000-0002-2518-2803)
- Julio Flores‐González (ORCID: https://orcid.org/0000-0003-4707-718X)
- Karen Medina‐Quero (ORCID: https://orcid.org/0000-0002-8663-6610)
- Leslie Chávez‐Galán (ORCID: https://orcid.org/0000-0002-2334-0361)
- Fernando Manuel Sosa-Gómez
- Carlos Peña‐Bates
- Enrique Espinosa (ORCID: https://orcid.org/0000-0002-3231-1626)
- Miguel Salazar
Institutions
- Instituto Nacional de Enfermedades Respiratorias (MX)
- Universidad del Ejército y Fuerza Aérea (MX)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1566449
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Institute of Nuclear Energy Research