Fruit-specific overexpression of lipoyl synthase increases both bound and unbound lipoic acid and alters the metabolome of tomato fruits
In addition, as the overexpression of <i>SlLIP1</i> results in lower transcript levels of <i>E2 PDH</i> and <i>E2 kGDH</i>, and enhanced amounts of LA-bound targets, we speculate that the proportion of unlipoylated E2 subunits of PDH and kGDH may have decreased. This work could assist in obtaining crops with a higher LA content and therefore improved health benefits.
Authors
- Felipe Uribe (ORCID: https://orcid.org/0000-0002-3894-0327)
- María Paz Covarrubias (ORCID: https://orcid.org/0000-0001-7575-4382)
- Pamela Cabedo
- Michael Handford (ORCID: https://orcid.org/0000-0003-0969-3192)
- Daniela Arias-G
Institutions
- University of Chile (CL)
Publication Details
- Journal
- Frontiers in Plant Science
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fpls.2025.1545011
- Citations
- 2
- Primary Topic
- Biochemical Acid Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.22
Funders
- University of North Texas
- Agencia Nacional de Investigación y Desarrollo