Impact of stool transplantation and metformin on polyp reduction and inflammation in an APC Min mouse model
Stool transplantation combined with metformin reduces polyp burden in APC Min mice through gut microbiota modulation and localized immune activation. These findings support the therapeutic potential of this combination treatment for familial adenomatous polyposis.
Authors
- E. Lee (ORCID: https://orcid.org/0000-0002-0746-8883)
- Seun Ja Park (ORCID: https://orcid.org/0000-0003-3217-5115)
- Jae Hyun Kim (ORCID: https://orcid.org/0000-0002-4272-8003)
- Yeon Ji Kim
- J. Lee
Institutions
- Kosin University (KR)
Publication Details
- Journal
- Intestinal Research
- Published
- 2025-05-19
- DOI
- https://doi.org/10.5217/ir.2025.00011
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea