Effects of unpredictable chronic mild stress of female rats before pregnancy on morphine-induced antinociceptive tolerance in offspring
Maternal UCMS increased oxidative stress markers in the ovaries and might relate to altered morphine antinociceptive potency in offspring, suggesting epigenetic effects of parental stress on pain management in future generations.
Authors
- Nahid Khodayari
- Masoumeh Gholami (ORCID: https://orcid.org/0000-0002-6746-0488)
- Mehdi Sadegh (ORCID: https://orcid.org/0000-0001-5791-2463)
- Nastaran Rashidi (ORCID: https://orcid.org/0000-0002-5570-9805)
- Mahdi Khorsand Ghaffari (ORCID: https://orcid.org/0000-0001-6165-4989)
- Hadi Karami (ORCID: https://orcid.org/0000-0002-4975-8731)
Institutions
- Arak University of Medical Sciences (IR)
Publication Details
- Journal
- The Korean journal of pain
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3344/kjp.24403
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Arak University of Medical Sciences