Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation

This study identifies <i>Vanin-1 (VNN1)</i> as a potential biomarker for systemic inflammation and highlights the role of <i>Plasminogen Activator, Tissue Type (PLAT)</i> in vascular dysfunction, emphasizing the critical importance of glycemic control in mitigating molecular and clinical dysregulation. These findings underscore the need for personalized, sex-specific strategies to manage these comorbidities effectively.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-05-19
DOI
https://doi.org/10.3389/fendo.2025.1574392
Citations
3
Primary Topic
Neurological diseases and metabolism
Type
article
Field-Weighted Citation Impact
2.53
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article

Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation

Olalekan A. Agede, Peace Ngozi Okoro, Chidiebere Valentine Ugwueze, J K Olarinoye et al.
3 citations
Frontiers in Endocrinology
Neurological diseases and metabolism
2.53
article

Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation

Olalekan A. Agede, Peace Ngozi Okoro, Chidiebere Valentine Ugwueze, J K Olarinoye, George Oche Ambrose, Victor Emmanuel Obaro
article en
3 citations

Abstract

This study identifies <i>Vanin-1 (VNN1)</i> as a potential biomarker for systemic inflammation and highlights the role of <i>Plasminogen Activator, Tissue Type (PLAT)</i> in vascular dysfunction, emphasizing the critical importance of glycemic control in mitigating molecular and clinical dysregulation. These findings underscore the need for personalized, sex-specific strategies to manage these comorbidities effectively.

Frontiers in EndocrinologyVol. 16
University of Ilorin (NG), Funai Electric (Japan) (JP), Federal Medical Centre (NG), University of Ilorin Teaching Hospital (NG), Federal Teaching Hospital Abakaliki (NG), University of Northern Colorado (US), Ebonyi State University (NG)
Good health and well-being
Openalex Percentile: Top 11%
Neurological diseases and metabolism
2.53
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