Regulation of interleukin-1 beta gene expression and its function of defense mechanism in rumen epithelial cells from pre- and postweaning calves
These results suggest that IL-1β induction by SCFAs, LPS, and flagellin, which increase in the rumen due to environmental changes, promotes cell proliferation in damaged rumen epithelium and contributes to its defense mechanism by upregulating CCL5 expression.
Authors
- Sanggun Roh (ORCID: https://orcid.org/0000-0003-1092-5691)
- Koki Nishihara (ORCID: https://orcid.org/0000-0003-1307-3551)
- Natsuki Sugiyama (ORCID: https://orcid.org/0000-0001-5299-0761)
- Huseong Lee (ORCID: https://orcid.org/0000-0003-1931-2007)
- Satoshi Haga (ORCID: https://orcid.org/0000-0002-7408-015X)
- Minji Kim (ORCID: https://orcid.org/0000-0001-6660-0197)
Institutions
- Tohoku University (JP)
Publication Details
- Journal
- Animal Bioscience
- Published
- 2025-05-18
- DOI
- https://doi.org/10.5713/ab.25.0042
- Primary Topic
- Effects of Environmental Stressors on Livestock
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Rural Development Administration
- Japan Society for the Promotion of Science