CD28 and CTLA4 polymorphisms associated with ankylosing spondylitis: a study in the context of HLA-B27
The elevated frequencies of specific alleles in AS patients compared to controls highlight the potential involvement of these SNPs as key factors in the pathogenesis of AS, offering new insights into the genetic mechanisms underlying the disease.
Authors
- Fang-Ping Hsu
- Grace Wu (ORCID: https://orcid.org/0000-0002-5413-2768)
- Wei-Tzu Lin (ORCID: https://orcid.org/0000-0002-6102-0545)
- Kuang‐Hui Yu (ORCID: https://orcid.org/0000-0001-6251-0231)
- Ding‐Ping Chen (ORCID: https://orcid.org/0000-0001-5578-6010)
- Chia-Ju Yang
Institutions
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- BMC Immunology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12865-025-00720-9
- Citations
- 1
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- Chang Gung Medical Foundation
- Chang Gung Memorial Hospital, Linkou