Impact of baseline 18F-flotufolastat PET bone tumor volume for prognosticating severe hematologic toxicity in patients with metastatic castration-resistant prostate Cancer receiving 177Lu-PSMA-targeted radioligand therapy

Baseline <sup>18</sup>F-flotufolastat-PET metrics and pretherapeutic clinical parameters are key prognostic factors for severe hematologic toxicity in mCRPC patients treated with [<sup>177</sup>Lu]Lu-PSMA-I&T.

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Publication Details

Journal
European Journal of Nuclear Medicine and Molecular Imaging
Published
2025-05-18
DOI
https://doi.org/10.1007/s00259-025-07200-7
Primary Topic
Prostate Cancer Treatment and Research
Type
article
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article

Impact of baseline 18F-flotufolastat PET bone tumor volume for prognosticating severe hematologic toxicity in patients with metastatic castration-resistant prostate Cancer receiving 177Lu-PSMA-targeted radioligand therapy

Robert Tauber, Matthias Heck, Isabel Rauscher, Matthias Eiber et al.
European Journal of Nuclear Medicine and Molecular Imaging
Prostate Cancer Treatment and Research
article

Impact of baseline 18F-flotufolastat PET bone tumor volume for prognosticating severe hematologic toxicity in patients with metastatic castration-resistant prostate Cancer receiving 177Lu-PSMA-targeted radioligand therapy

Robert Tauber, Matthias Heck, Isabel Rauscher, Matthias Eiber, Calogero D ́Alessandria, Bernhard Haller, Amir Karimzadeh, Stefan Hein, Kimberley J. Hansen
article en

Abstract

Baseline <sup>18</sup>F-flotufolastat-PET metrics and pretherapeutic clinical parameters are key prognostic factors for severe hematologic toxicity in mCRPC patients treated with [<sup>177</sup>Lu]Lu-PSMA-I&T.

European Journal of Nuclear Medicine and Molecular ImagingVol. 52(12)
Technical University of Munich (DE)
Good health and well-being
Openalex Percentile: Top 82%
Prostate Cancer Treatment and Research
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