Last decade of advances in gastric neuroendocrine tumors: Innovations, challenges, and future directions

G-NETs require tailored diagnosis and treatment based on type and stage. Types I and II generally have better prognosis, while types III and IV are linked to poorer outcomes due to invasion and metastasis. Treatment strategies vary from ER for type I to extensive surgery for type III. Emerging therapies, like somatostatin analogs and peptide-receptor radionuclide therapies, show promise in advanced cases. Further research is essential to improve early diagnosis and treatment, particularly for high-risk lesions.

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Publication Details

Journal
World Journal of Clinical Oncology
Published
2025-05-19
DOI
https://doi.org/10.5306/wjco.v16.i5.104577
Citations
2
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
Field-Weighted Citation Impact
2.71
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article

Last decade of advances in gastric neuroendocrine tumors: Innovations, challenges, and future directions

Dimitrios Ragias, Grigorios Christodoulidis, Dimitrios Zacharoulis, Marina Nektaria Kouliou et al.
2 citations
World Journal of Clinical Oncology
Neuroendocrine Tumor Research Advances
2.71
article

Last decade of advances in gastric neuroendocrine tumors: Innovations, challenges, and future directions

Dimitrios Ragias, Grigorios Christodoulidis, Dimitrios Zacharoulis, Marina Nektaria Kouliou, Dimitrios Chatziisaak, Dimitrios Schizas, Eirini Sara Agko
article en
2 citations

Abstract

G-NETs require tailored diagnosis and treatment based on type and stage. Types I and II generally have better prognosis, while types III and IV are linked to poorer outcomes due to invasion and metastasis. Treatment strategies vary from ER for type I to extensive surgery for type III. Emerging therapies, like somatostatin analogs and peptide-receptor radionuclide therapies, show promise in advanced cases. Further research is essential to improve early diagnosis and treatment, particularly for high-risk lesions.

World Journal of Clinical OncologyVol. 16(5)
National and Kapodistrian University of Athens (GR)
Good health and well-being
Openalex Percentile: Top 10%
Neuroendocrine Tumor Research Advances
2.71
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