Natural compound rosmarinic acid displays anti-tumor activity in colorectal cancer cells by suppressing nuclear factor-kappa B signaling
Our results indicate that RA inhibits NF-κB signaling and induces apoptosis in CRC cells. It enhances the cytotoxic actions of chemotherapeutics and might help to improve the chemotherapy of CRC.
Authors
- Wen‐Yue Liu (ORCID: https://orcid.org/0000-0003-1454-7077)
- Xuan Wang (ORCID: https://orcid.org/0000-0002-1542-3642)
- Wei‐Cheng You (ORCID: https://orcid.org/0000-0003-2190-1812)
- Xin Xu (ORCID: https://orcid.org/0000-0002-0479-6988)
- Tao Zhang (ORCID: https://orcid.org/0000-0002-8622-9169)
- Han Wang (ORCID: https://orcid.org/0000-0001-8042-1232)
- Yili Yang (ORCID: https://orcid.org/0000-0003-4780-050X)
- Kunkun Han
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- World Journal of Clinical Oncology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.5306/wjco.v16.i5.105341
- Citations
- 7
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 5.64