Functional heterogeneity and clinical implications of CD4+ T cell subtypes in high-grade serous ovarian carcinoma
Treg3 cells drive immune suppression and tumor progression in HGSOC, making them a key immunotherapy target. Their adnexal enrichment highlights the need for tissue-specific immune profiling in precision treatment.
Authors
- Li Tan (ORCID: https://orcid.org/0000-0002-4397-090X)
- Beilei Zhang (ORCID: https://orcid.org/0000-0003-1384-0175)
- Xiaoting Liu (ORCID: https://orcid.org/0000-0001-6313-4338)
- Ling He
- Wei Gao (ORCID: https://orcid.org/0000-0002-5043-6692)
- Zhongming Wang (ORCID: https://orcid.org/0009-0007-3573-4986)
Institutions
- Central South University (CN)
- Second People Hospital of Hunan (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- World Journal of Clinical Oncology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.5306/wjco.v16.i5.104138
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.80