Nano particle loaded EZH2 inhibitors: Increased efficiency and reduced toxicity for malignant solid tumors
Albumin-based EZH2i NPs have potent anti-cancer efficacy with tolerable adverse effects, providing promising opportunity for future clinical translation in treating solid tumors.
Authors
- Yuanjun Tang (ORCID: https://orcid.org/0000-0002-6467-2549)
- Lixiang Xue (ORCID: https://orcid.org/0000-0003-1507-7193)
- Qianqian Yin (ORCID: https://orcid.org/0000-0002-8403-0236)
- Zhengyang Guo (ORCID: https://orcid.org/0009-0004-0363-6765)
- Tengrui Zhang
- Lin Meng (ORCID: https://orcid.org/0000-0001-9787-9936)
- Yunyun Guo (ORCID: https://orcid.org/0000-0002-1664-9125)
- Yang Liu (ORCID: https://orcid.org/0000-0003-1145-7412)
- Xuedi Cao
- Yan Wang (ORCID: https://orcid.org/0000-0002-8678-973X)
- Yuqing Wang (ORCID: https://orcid.org/0009-0006-2028-8138)
- Xian Qi (ORCID: https://orcid.org/0000-0002-8264-0794)
- Rui Cheng (ORCID: https://orcid.org/0009-0006-3804-6970)
- Jiaqi Huang (ORCID: https://orcid.org/0000-0002-6514-3075)
- Yiwei Peng
Institutions
- Peking University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Peking University People's Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Journal of Translational Internal Medicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1515/jtim-2025-0020
- Citations
- 5
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital
- National Key Research and Development Program of China