When Neisseria meningitidis Strikes an Immunocompetent Host and Purpura Fulminans Results
Purpura fulminans (PF) is a rapidly progressive, life-threatening condition marked by ecchymotic, tender, and symmetric skin lesions, often resulting from disseminated intravascular coagulation (DIC) secondary to infectious or non-infectious etiologies. PF usually occurs in immunocompromised hosts and is associated with a high mortality rate. Here, we highlight a case of an elderly immunocompetent woman with <i>Neisseria meningitis-mediated</i> DIC and subsequent PF. Her case underscores the importance of early intervention in managing this rare but deadly condition in order to ensure optimal survival outcomes. Early intervention for PF with DIC includes the timely administration of antibiotics, steroids, and anticoagulants, along with addressing the underlying consumptive coagulopathy.
Authors
- Andy Li (ORCID: https://orcid.org/0009-0000-1990-928X)
- Prachi Saxena (ORCID: https://orcid.org/0000-0002-5161-9829)
- Aye M Thida (ORCID: https://orcid.org/0000-0002-9308-4682)
- Jordonna Brown
- Ekenedilichukwu N Nnadi
Institutions
- State University of New York (US)
- SUNY Downstate Health Sciences University (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-05-18
- DOI
- https://doi.org/10.7759/cureus.84350
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00