Outcomes of Descemet Membrane Detachment Repair with Intracameral C3F8 Following Cataract Surgery: A Retrospective Analysis

Background: Descemet membrane detachment (DMD) is a significant postoperative complication of cataract surgery.Early surgical intervention with intracameral gas tamponade, particularly C3F8, has shown promising outcomes.This study evaluates anatomical and visual outcomes following descemetopexy using isoexpansile 14% perfluoropropane (C3F8) gas.Methods: A retrospective review was conducted of 11 patients with DMD after cataract surgery treated with intracameral C3F8.Data collected included demographic details, interval between cataract surgery and descemetopexy, preoperative and postoperative visual acuity (logMAR), and corneal edema measurements.Statistical analysis was performed using paired t-tests.Results: The mean patient age was 68.626.58years.Gender distribution was equal.Left eye involvement was predominant (62.5%).The mean interim period between cataract surgery and descemetopexy was 41.5101.46days.Vision improved significantly from a mean preoperative logMAR of 1.320.66 to postoperative 0.280.32(p<0.001).Corneal edema reduced significantly from 935.0073.72 m to 573.6894.42m (p<0.001).Complete DM reattachment was achieved in 10 of 11 patients.Conclusion: Descemetopexy using isoexpansile C3F8 following cataract surgery yields favorable anatomical and visual outcomes.It should be considered as a primary intervention for DMD before resorting to more complex surgeries.