The possibility of preventing the development of adhesions

Aim . To study the possibilities of preventing the development of adhesions in clinical practice. Methods . The present study analyzed current sources, both domestic and foreign literature on various ways of preventing the development of adhesions and the effectiveness of these methods. Results . According to the definition of the Association of Surgeons, adhesions are a multifactorial pathological process based on various morphofunctional disorders of organs and body systems. Currently, there are several main ways to reduce the severity of the adhesive process: reduction of injury to the peritoneum, the use of drugs that affect the formation of fibrin and fibrinolysis, effective hemostasis, prevention of tissue drying and the use of barriers that prevent adhesions. Conclusion . Despite the extensive knowledge of the pathophysiology of adhesions, strategies to address the problem of adhesions have not yet been developed. The methods discussed in this study, although promising, do not show results that would allow their widespread implementation in clinical practice.

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Publication Details

Journal
Surgical practice (Russia)
Published
2025-05-17
DOI
https://doi.org/10.5922/2223-2427-2025-10-1-4
Primary Topic
Intestinal and Peritoneal Adhesions
Type
article
Field-Weighted Citation Impact
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article

The possibility of preventing the development of adhesions

V. P. Stepanenko, E. S. Petrukhina, А. Н. Сергеев, А. М. Morozov et al.
Surgical practice (Russia)
Intestinal and Peritoneal Adhesions
article

The possibility of preventing the development of adhesions

V. P. Stepanenko, E. S. Petrukhina, А. Н. Сергеев, А. М. Morozov, E. Fisyuk, A. A. Bagdasarov, Nikolay Sergeev
article en

Abstract

Aim . To study the possibilities of preventing the development of adhesions in clinical practice. Methods . The present study analyzed current sources, both domestic and foreign literature on various ways of preventing the development of adhesions and the effectiveness of these methods. Results . According to the definition of the Association of Surgeons, adhesions are a multifactorial pathological process based on various morphofunctional disorders of organs and body systems. Currently, there are several main ways to reduce the severity of the adhesive process: reduction of injury to the peritoneum, the use of drugs that affect the formation of fibrin and fibrinolysis, effective hemostasis, prevention of tissue drying and the use of barriers that prevent adhesions. Conclusion . Despite the extensive knowledge of the pathophysiology of adhesions, strategies to address the problem of adhesions have not yet been developed. The methods discussed in this study, although promising, do not show results that would allow their widespread implementation in clinical practice.

Surgical practice (Russia)(1)
Tver State Medical University (RU), Regional Children's Clinical Hospital No. 1 (RU)
Openalex Percentile: Top 81%
Intestinal and Peritoneal Adhesions
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