Current and Emerging Formulations in Topical Antifungal Therapy: A Comparative Overview

Fungal infections, a widespread issue, affect millions of people worldwide and can range from minor skin diseases to serious, sometimes fatal infections. Traditional topical treatments, such as creams, gels, sprays, and ointments, are popular for treating fungal infections due to their ease of use, fewer adverse effects, and safety. However, they have drawbacks like frequent application, inability to stay on the skin for extended periods, and uneven efficacy. New drug delivery technologies, such as liposomes, nanoparticles, and microemulsions, are transforming the treatment of fungal diseases by improving drug interaction with the skin, enhancing patient comfort, and reducing side effects. Keywords: Fungal infections, Topical antifungal therapy, Nanotechnology, Therapeutic efficacy.