Green tea epigallocatechin gallate attenuate metabolic dysfunction-associated steatotic liver disease by regulation of pyroptosis
These results suggest that EGCG may attenuate MASLD in larval and adult zebrafish induced by 15 consecutive days HFD, which is potentially mediated by modulating the Nrf2/NF-κB/NLRP3 signaling pathway which relieve pyroptosis.
Authors
- Qiao Zhang (ORCID: https://orcid.org/0000-0001-5570-1507)
- Shuxiang Wang (ORCID: https://orcid.org/0000-0001-7649-8878)
- Shuangshuang Wang (ORCID: https://orcid.org/0000-0002-2072-0270)
- Jie Zhang (ORCID: https://orcid.org/0000-0002-0800-2022)
- Ting Zhang (ORCID: https://orcid.org/0000-0001-8074-8999)
- Minghui Zi
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-05-17
- DOI
- https://doi.org/10.1186/s12944-025-02596-5
- Citations
- 6
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- National Natural Science Foundation of China