In vivo protein half-life analysis identifies the SREBF1-SLC27a5 axis governs antioxidant response in preclinical alcoholic rat model
Alcohol abstinence modulates protein half-lives through Srebf1-Slc27a5 axis, reducing inflammation, steatosis, and oxidative stress, potentially aiding in alcohol-induced liver damage treatment.
Authors
- Ranjan Kumar Nanda (ORCID: https://orcid.org/0000-0002-2163-4411)
- Jaswinder Singh Maras (ORCID: https://orcid.org/0000-0003-3938-362X)
- Neha Sharma (ORCID: https://orcid.org/0000-0002-7239-6345)
- Sadam H. Bhat (ORCID: https://orcid.org/0000-0002-5466-4799)
- Abhishak Gupta (ORCID: https://orcid.org/0000-0002-5759-1775)
- Babu Mathew (ORCID: https://orcid.org/0000-0003-3956-8659)
- Vasundhra Bindal
- Sushmita Pandey
- Shvetank Sharma (ORCID: https://orcid.org/0000-0001-7139-2011)
- Anupama Kumari (ORCID: https://orcid.org/0000-0003-0579-5706)
- Sanjay Yadav (ORCID: https://orcid.org/0000-0003-3765-0691)
- Shweta Chaudhary (ORCID: https://orcid.org/0000-0002-0041-281X)
- Gaurav Tripathi (ORCID: https://orcid.org/0000-0002-1820-6547)
- Nupur Sharma
- Manisha Yadav
- Vipul Sharma
Institutions
- Institute of Liver and Biliary Sciences (IN)
- International Centre for Genetic Engineering and Biotechnology (IN)
- Artemis Hospitals (IN)
Publication Details
- Journal
- Redox Biology
- Published
- 2025-05-17
- DOI
- https://doi.org/10.1016/j.redox.2025.103674
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Council for Scientific and Industrial Research, South Africa
- Department of Science and Technology, Ministry of Science and Technology, India
- Defence Science and Technology Group