Esketamine mitigates lung injury in COPD rat models under mechanical ventilation: An RNA-sequencing and bioinformatics analysis of serum exosome miRNA profiles
Esketamine demonstrates significant potential to alleviate lung injury in COPD rat models subjected to mechanical ventilation, likely through modulating critical pathways related to inflammation, fibrosis, and cellular stress. Further research is needed to confirm these findings in clinical settings.
Authors
- Ang Liu (ORCID: https://orcid.org/0009-0000-5558-0856)
- Bin Su (ORCID: https://orcid.org/0000-0002-7236-9857)
- Chui-Yu Li
- Zhi-Yuan Chen
- Xiaoqi Zhang (ORCID: https://orcid.org/0000-0003-0707-0928)
- Gao Xiao-hua
- Wen-Xi Xie
- Yu Mao
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Heze Municipal Hospital (CN)
Publication Details
- Journal
- Gene
- Published
- 2025-05-17
- DOI
- https://doi.org/10.1016/j.gene.2025.149571
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42