Perioperative changes in quality of life in cirotic patients with portal splenopathy of surgical interest
Portal splenopathy associated with severe symptomatic hypersplenism is a frequent complication of liver cirrhosis [1, 4], often of surgical interest. Laparoscopic splenectomy and esophagogastric devascularization has gained a prominent position in the field of portal hypertension. We evaluated 156 cirrhotic patients surgically assisted in the Clinic for portal splenopathy (year 2013-2023), laparoscopic (SPLL, n=64) or conventional open (SPLT, n=92) approach, associated in 69.9% of cases (109/159), with endoscopic variceal ligation (LVE). The clinical-endo-imaging characteristics of the patients and the quality of life, according to the chronic liver disease questionnaire (SF-LDQOL), were compared between the groups, depending on the surgical method. The results demonstrate that DVA+SPL has a positive impact on the quality of life (QoL-quality of life), constant 12-18 months after the operation. The lower QoL score, for the subdomains studied 3-5 years postoperatively, can be explained by the accumulation of risk factors dominated by liver depression and possible complications.
Authors
- Cazacov Vladimir
- Alexandru Ferdohleb (ORCID: https://orcid.org/0000-0003-3290-8139)
- Dumitru Cazacu (ORCID: https://orcid.org/0000-0003-3146-8506)
- Calina Bugor (ORCID: https://orcid.org/0000-0003-3035-710X)
- Mariana Ous-Cebotar (ORCID: https://orcid.org/0009-0005-0112-0404)
- Vlad Moisei
Institutions
- Hospital Regional de Antofagasta (CL)
- Nicolae Testemițanu State University of Medicine and Pharmacy (MD)
Publication Details
- Journal
- Bulletin of the Academy of Sciences of Moldova Medical Sciences
- Published
- 2024-12-01
- DOI
- https://doi.org/10.52692/1857-0011.2024.2-79.22
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00