Perioperative changes in quality of life in cirotic patients with portal splenopathy of surgical interest

Portal splenopathy associated with severe symptomatic hypersplenism is a frequent complication of liver cirrhosis [1, 4], often of surgical interest. Laparoscopic splenectomy and esophagogastric devascularization has gained a prominent position in the field of portal hypertension. We evaluated 156 cirrhotic patients surgically assisted in the Clinic for portal splenopathy (year 2013-2023), laparoscopic (SPLL, n=64) or conventional open (SPLT, n=92) approach, associated in 69.9% of cases (109/159), with endoscopic variceal ligation (LVE). The clinical-endo-imaging characteristics of the patients and the quality of life, according to the chronic liver disease questionnaire (SF-LDQOL), were compared between the groups, depending on the surgical method. The results demonstrate that DVA+SPL has a positive impact on the quality of life (QoL-quality of life), constant 12-18 months after the operation. The lower QoL score, for the subdomains studied 3-5 years postoperatively, can be explained by the accumulation of risk factors dominated by liver depression and possible complications.

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Publication Details

Journal
Bulletin of the Academy of Sciences of Moldova Medical Sciences
Published
2024-12-01
DOI
https://doi.org/10.52692/1857-0011.2024.2-79.22
Primary Topic
Liver Disease and Transplantation
Type
article
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article

Perioperative changes in quality of life in cirotic patients with portal splenopathy of surgical interest

Cazacov Vladimir, Alexandru Ferdohleb, Dumitru Cazacu, Calina Bugor et al.
Bulletin of the Academy of Sciences of Moldova Medical Sciences
Liver Disease and Transplantation
article

Perioperative changes in quality of life in cirotic patients with portal splenopathy of surgical interest

Cazacov Vladimir, Alexandru Ferdohleb, Dumitru Cazacu, Calina Bugor, Mariana Ous-Cebotar, Vlad Moisei
article en

Abstract

Portal splenopathy associated with severe symptomatic hypersplenism is a frequent complication of liver cirrhosis [1, 4], often of surgical interest. Laparoscopic splenectomy and esophagogastric devascularization has gained a prominent position in the field of portal hypertension. We evaluated 156 cirrhotic patients surgically assisted in the Clinic for portal splenopathy (year 2013-2023), laparoscopic (SPLL, n=64) or conventional open (SPLT, n=92) approach, associated in 69.9% of cases (109/159), with endoscopic variceal ligation (LVE). The clinical-endo-imaging characteristics of the patients and the quality of life, according to the chronic liver disease questionnaire (SF-LDQOL), were compared between the groups, depending on the surgical method. The results demonstrate that DVA+SPL has a positive impact on the quality of life (QoL-quality of life), constant 12-18 months after the operation. The lower QoL score, for the subdomains studied 3-5 years postoperatively, can be explained by the accumulation of risk factors dominated by liver depression and possible complications.

Bulletin of the Academy of Sciences of Moldova Medical SciencesVol. 79(2)
Hospital Regional de Antofagasta (CL), Nicolae Testemițanu State University of Medicine and Pharmacy (MD)
Openalex Percentile: Top 61%
Liver Disease and Transplantation
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