Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma

Question Tumor response to SIRT can change; there is limited evidence on the evolution of the imaging appearance of HCC following SIRT. Findings Sixty-four and five-tenths of early nonprogressing lesions regressed to nonviable, and 91.2% of early nonviable lesions remained free of viability. LR-TR category assignment agreement was moderate with CT but almost perfect with MRI. Clinical relevance SIRT induced a delayed and sustained response in HCC, underscoring the necessity of dynamic evaluation of long-term changes in treated lesions. MRI with subtraction imaging may be preferred over CT for long-term monitoring, which may help prevent premature retreatment decisions.

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Publication Details

Journal
European Radiology
Published
2025-05-17
DOI
https://doi.org/10.1007/s00330-025-11659-1
Citations
6
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
8.16

Funders

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article

Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma

Yuanan Wu, Hanyu Jiang, Hyo‐Cheol Kim, Jeongin Yoo et al.
6 citations
European Radiology
Radiomics and Machine Learning in Medical Imaging
8.16
article

Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma

Yuanan Wu, Hanyu Jiang, Hyo‐Cheol Kim, Jeongin Yoo, Hyo‐Jin Kang, Jae Hyun Kim, Jeong Min Lee, Hong Wei, Rongbo Liu
article en
6 citations

Abstract

Question Tumor response to SIRT can change; there is limited evidence on the evolution of the imaging appearance of HCC following SIRT. Findings Sixty-four and five-tenths of early nonprogressing lesions regressed to nonviable, and 91.2% of early nonviable lesions remained free of viability. LR-TR category assignment agreement was moderate with CT but almost perfect with MRI. Clinical relevance SIRT induced a delayed and sustained response in HCC, underscoring the necessity of dynamic evaluation of long-term changes in treated lesions. MRI with subtraction imaging may be preferred over CT for long-term monitoring, which may help prevent premature retreatment decisions.

European RadiologyVol. 35(11)
Seoul National University (KR), University of Electronic Science and Technology of China (CN), Sichuan University (CN), New Generation University College (ET), Seoul National University Hospital (KR), West China Hospital of Sichuan University (CN), National University College (PR)
Seoul National University
Openalex Percentile: Top 2%
Radiomics and Machine Learning in Medical Imaging
8.16
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Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma — Yuanan Wu, Hanyu Jiang, et al. · European Radiology (2025) | TGRS Research Map | TGRS