Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma
Question Tumor response to SIRT can change; there is limited evidence on the evolution of the imaging appearance of HCC following SIRT. Findings Sixty-four and five-tenths of early nonprogressing lesions regressed to nonviable, and 91.2% of early nonviable lesions remained free of viability. LR-TR category assignment agreement was moderate with CT but almost perfect with MRI. Clinical relevance SIRT induced a delayed and sustained response in HCC, underscoring the necessity of dynamic evaluation of long-term changes in treated lesions. MRI with subtraction imaging may be preferred over CT for long-term monitoring, which may help prevent premature retreatment decisions.
Authors
- Yuanan Wu (ORCID: https://orcid.org/0000-0003-4513-1357)
- Hanyu Jiang (ORCID: https://orcid.org/0000-0002-7726-1618)
- Hyo‐Cheol Kim (ORCID: https://orcid.org/0000-0002-6016-247X)
- Jeongin Yoo (ORCID: https://orcid.org/0000-0002-3267-2544)
- Hyo‐Jin Kang (ORCID: https://orcid.org/0000-0002-6771-2112)
- Jae Hyun Kim
- Jeong Min Lee (ORCID: https://orcid.org/0000-0003-0561-8777)
- Hong Wei (ORCID: https://orcid.org/0000-0002-1561-1512)
- Rongbo Liu (ORCID: https://orcid.org/0000-0003-0135-7514)
Institutions
- Seoul National University (KR)
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- New Generation University College (ET)
- Seoul National University Hospital (KR)
- West China Hospital of Sichuan University (CN)
- National University College (PR)
Publication Details
- Journal
- European Radiology
- Published
- 2025-05-17
- DOI
- https://doi.org/10.1007/s00330-025-11659-1
- Citations
- 6
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 8.16
Funders
- Seoul National University