Entrectinib-induced pericarditis with cardiac tamponade in a patient with neurotrophic tropomyosin receptor kinase 1 fusion-positive breast cancer
To our knowledge, this is the first reported case of entrectinib-induced pericarditis complicated by cardiac tamponade. Patients should be closely monitored for signs of pericarditis and cardiac tamponade at the start of entrectinib therapy. In patients who develop cardiovascular toxicity due to entrectinib, larotrectinib may be considered as an alternative treatment.
Authors
- Yutaro Yoshitomi (ORCID: https://orcid.org/0009-0005-8791-1513)
- Akihiko Shimomura (ORCID: https://orcid.org/0000-0002-2557-8170)
- Yukino Kawamura (ORCID: https://orcid.org/0000-0002-4708-8201)
- Tomoko Taniyama
- Yukio Hiroi (ORCID: https://orcid.org/0000-0001-5088-7656)
- Atsumasa Kurozumi (ORCID: https://orcid.org/0000-0002-3877-1770)
- Aki Aoyama
- Chikako Shimizu
- Shuji Kubota
Institutions
- National Center for Global Health and Medicine (JP)
Publication Details
- Journal
- Case Reports in Oncology
- Published
- 2025-05-17
- DOI
- https://doi.org/10.1159/000546503
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00