Rapid Progression of Dermatomyositis in an Elderly Patient With Oropharyngeal and Pulmonary Involvement: A Case Report

Dermatomyositis is a rare autoimmune condition characterized by proximal muscle weakness and distinctive skin manifestations, with increased age being a significant negative prognostic factor. This case presents a 79-year-old male who presented to the emergency department with a six-week history of fatigue, weight loss, progressive symmetrical muscle weakness, and hallmark rashes, including a heliotrope rash and Gottron papules. Despite discontinuing statin therapy, thought to be a potential contributing factor to his symptoms, his condition quickly worsened, and investigations confirmed dermatomyositis through positive autoantibodies and imaging. Treatment with corticosteroids was initiated, but he continued to deteriorate rapidly, leading to dysphagia, respiratory distress, and aspiration pneumonia, which ultimately resulted in death just 28 days after initial presentation. This case emphasizes the potential for rapid progression of dermatomyositis in elderly patients, particularly those with oropharyngeal and pulmonary involvement, and highlights the importance of early recognition and multidisciplinary management.

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Publication Details

Journal
Cureus
Published
2025-05-17
DOI
https://doi.org/10.7759/cureus.84267
Citations
1
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
1.35
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article

Rapid Progression of Dermatomyositis in an Elderly Patient With Oropharyngeal and Pulmonary Involvement: A Case Report

Elizabeth Broad
1 citations
Cureus
Inflammatory Myopathies and Dermatomyositis
1.35
article

Rapid Progression of Dermatomyositis in an Elderly Patient With Oropharyngeal and Pulmonary Involvement: A Case Report

Elizabeth Broad
article en
1 citations

Abstract

Dermatomyositis is a rare autoimmune condition characterized by proximal muscle weakness and distinctive skin manifestations, with increased age being a significant negative prognostic factor. This case presents a 79-year-old male who presented to the emergency department with a six-week history of fatigue, weight loss, progressive symmetrical muscle weakness, and hallmark rashes, including a heliotrope rash and Gottron papules. Despite discontinuing statin therapy, thought to be a potential contributing factor to his symptoms, his condition quickly worsened, and investigations confirmed dermatomyositis through positive autoantibodies and imaging. Treatment with corticosteroids was initiated, but he continued to deteriorate rapidly, leading to dysphagia, respiratory distress, and aspiration pneumonia, which ultimately resulted in death just 28 days after initial presentation. This case emphasizes the potential for rapid progression of dermatomyositis in elderly patients, particularly those with oropharyngeal and pulmonary involvement, and highlights the importance of early recognition and multidisciplinary management.

CureusVol. 17(5)
St Helens and Knowsley Teaching Hospitals NHS Trust (GB)
Good health and well-being
Openalex Percentile: Top 20%
Inflammatory Myopathies and Dermatomyositis
1.35
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