Shared genetic architecture between leukocyte telomere length and Alzheimer’s disease
Our study identified specific shared loci between LTL and AD, providing new insights for polygenic overlap and molecular mechanisms, and highlighting new opportunities for future experimental validation.
Authors
- Hongxi Yang (ORCID: https://orcid.org/0000-0002-9545-5715)
- Qilong Tan
- Chenjie Xu (ORCID: https://orcid.org/0000-0002-8997-9299)
- Z.P. Cao (ORCID: https://orcid.org/0009-0007-0426-4643)
Institutions
- Hangzhou Normal University (CN)
- Sir Run Run Shaw Hospital (CN)
- Tianjin Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-05-17
- DOI
- https://doi.org/10.1186/s13195-025-01757-z
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province