Immune-microbiota dysregulation in maintenance hemodialysis: a 16S rRNA sequencing-based analysis of gut flora and T cell profiles
This study provides novel evidence linking gut microbial dysbiosis to immune impairment in MHD patients. The findings suggest that SCFA-producing bacteria are depleted in immunodeficient states, offering a potential target for microbiota-directed immunomodulatory therapies in ESRD.
Authors
- Xiuting Yang
- Yan Lv (ORCID: https://orcid.org/0000-0003-2141-1127)
- Xiaowu Sun
- Xiaohong Ren
Institutions
- Shanxi Medical University (CN)
- Shanxi Academy of Medical Sciences (CN)
- Tongji Hospital (CN)
- Pingliang People's Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1080/0886022x.2025.2498630
- Citations
- 3
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 4.19