Inhibition of caspase-1 by ginsenoside Rg1 ameliorates <scp>d</scp> -gal-induced renal aging and injury through suppression of oxidative stress and inflammation
The findings in this study provide experimental support for the clinical application of ginsenoside Rg1 in kidney aging. The underlying mechanisms require further experimental validation.
Authors
- Meixia Fang (ORCID: https://orcid.org/0000-0001-5882-5783)
- Zhenyu Bai
- Ting Xie (ORCID: https://orcid.org/0000-0002-9958-3888)
- Jun Zhang (ORCID: https://orcid.org/0000-0003-1739-6462)
- Ya Xiao (ORCID: https://orcid.org/0000-0003-0655-9334)
- Xuejun Chen (ORCID: https://orcid.org/0000-0001-6124-7312)
- Tingting Guo (ORCID: https://orcid.org/0000-0002-4838-1450)
- Huiyu Liang
- Xiaoshan Zhao
- Jingying Zhong
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Zhujiang Hospital (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1080/0886022x.2025.2504634
- Citations
- 2
- Primary Topic
- Biomedical Research and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- National Natural Science Foundation of China
- Guangdong Medical Research Foundation
- Traditional Chinese Medicine Bureau of Guangdong Province
- Basic and Applied Basic Research Foundation of Guangdong Province