SERPINA3 in Diabetic Retinopathy: A Pilot Study Assessing the Impact of Prior COVID-19 Infection on Patients

Overall, SERPINA3 had poor sensitivity and specificity for identifying DR patients, and COVID-19 infection history significantly increased variance in SERPINA3 levels. Further investigation into the potential of SERPINA3 as DR biomarker should be sufficiently powered to account for the potentially confounding effects of COVID-19 infection.

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Publication Details

Journal
Current Eye Research
Published
2025-05-15
DOI
https://doi.org/10.1080/02713683.2025.2494795
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

SERPINA3 in Diabetic Retinopathy: A Pilot Study Assessing the Impact of Prior COVID-19 Infection on Patients

Ashok Sharma, Vikas Kumar, Shruti Sharma, Rebekah Robinson et al.
Current Eye Research
Retinal Diseases and Treatments
article

SERPINA3 in Diabetic Retinopathy: A Pilot Study Assessing the Impact of Prior COVID-19 Infection on Patients

Ashok Sharma, Vikas Kumar, Shruti Sharma, Rebekah Robinson, Eunheh Koh, Arthur S. Miller
article en

Abstract

Overall, SERPINA3 had poor sensitivity and specificity for identifying DR patients, and COVID-19 infection history significantly increased variance in SERPINA3 levels. Further investigation into the potential of SERPINA3 as DR biomarker should be sufficiently powered to account for the potentially confounding effects of COVID-19 infection.

Current Eye ResearchVol. 50(8)
Augusta University (US), Discovery Institute (US)
Good health and well-being
Openalex Percentile: Top 82%
Retinal Diseases and Treatments
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