Exploring the key ingredients and mechanisms of Banxia Xiexin decoction for the treatment of polycystic ovary syndrome based on network pharmacology and experimental validation
Five oxidative stress-related hub targets of BXD for PCOS were identified, including FOS, JUN, MAPK3, TP53 and HSP90AA1, while three key ingredients of BXD, quercetin, glycyrrhetinic acid A and naringenin, were uncovered.
Authors
- M Wang (ORCID: https://orcid.org/0000-0002-9550-9031)
- Richard Mprah (ORCID: https://orcid.org/0000-0001-8762-5481)
- Yingying Zhang (ORCID: https://orcid.org/0000-0003-3772-3942)
- Hai Bai (ORCID: https://orcid.org/0000-0003-4169-8161)
- Jing Huang (ORCID: https://orcid.org/0000-0002-6153-989X)
Institutions
- Xuzhou Medical College (CN)
- Shanxi Datong University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1080/07853890.2025.2503921
- Citations
- 4
- Primary Topic
- Healthcare and Venom Research
- Type
- article
- Field-Weighted Citation Impact
- 5.58