Evaluation of outcomes of duodenal ulcer perforation closure using single-port laparoscopic surgery

Objective: To investigate the clinical and paraclinical characteristics of patients with perforated duodenal ulcers and to evaluate the outcomes of single-port laparoscopic closure of the perforation. Subject and method: A cross-sectional descriptive study combined with a prospective interventional longitudinal follow-up was conducted on 87 patients with perforated duodenal ulcers who underwent single-port laparoscopic closure from January 2021 to January 2024. Result: Among the 87 patients, the mean age was 52.3 ± 10.7 years, with males accounting for 60.9%, primarily in the 41-60 age group (51.7%). A history of peptic ulcer disease was the most common comorbidity (36.8%). In 79.3% of cases, symptoms began abruptly within 12 hours, with abdominal pain (97.7%) and peritoneal signs (92.0%) as the predominant features. Most patients were classified as Boey score 0 (80.5%). The perforation was located on the anterior duodenal bulb in 63.2% of cases, with a size of 5-10 mm in 66.7%. Diagnosis was mainly based on upright abdominal X-rays (74.7%) and CT scans (67.8%). Closure was performed using an X-stitch in 63.2% of patients, with drain placement in 97.7%. The mean operative time was 74.5 minutes. The complication rate was low (4.5%), and no mortality was reported. Conclusion: Duodenal ulcer perforation predominantly affects middle-aged men and typically presents with classic clinical symptoms and a short onset time. Simple suture closure combined with drainage via single-port laparoscopy yields favorable surgical outcomes.