Oxcarbazepine Induced Rhabdomyolysis and Acute Kidney Injury: A Case Report

The cause of acute skeletal muscle damage, defined as rhabdomyolysis, is multifactorial. Medicines are prominent among the most important reasons. The clinical significance of rhabdomyolysis lies in the fact that it can cause acute kidney injury (AKI) in 10%-40% of patients. In this presented case, oxcarbazepine, which is a preferred drug in the treatment of epilepsy and also in neuropathic pain in clinical practice, triggered rhabdomyolysis and subsequently caused the development of AKI. Through this case report, we aimed to emphasize that some serious side effects should not be forgotten when prescribing drugs in clinical practice.

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Publication Details

Journal
Case Reports in Nephrology
Published
2025-01-01
DOI
https://doi.org/10.1155/crin/4168888
Primary Topic
Muscle and Compartmental Disorders
Type
article
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article

Oxcarbazepine Induced Rhabdomyolysis and Acute Kidney Injury: A Case Report

Nuray Can Usta, Sara Yavuz Ileri
Case Reports in Nephrology
Muscle and Compartmental Disorders
article

Oxcarbazepine Induced Rhabdomyolysis and Acute Kidney Injury: A Case Report

Nuray Can Usta, Sara Yavuz Ileri
article en

Abstract

The cause of acute skeletal muscle damage, defined as rhabdomyolysis, is multifactorial. Medicines are prominent among the most important reasons. The clinical significance of rhabdomyolysis lies in the fact that it can cause acute kidney injury (AKI) in 10%-40% of patients. In this presented case, oxcarbazepine, which is a preferred drug in the treatment of epilepsy and also in neuropathic pain in clinical practice, triggered rhabdomyolysis and subsequently caused the development of AKI. Through this case report, we aimed to emphasize that some serious side effects should not be forgotten when prescribing drugs in clinical practice.

Case Reports in NephrologyVol. 2025(1)
Uni Research (Norway) (NO), Ankara Onkoloji Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR)
Good health and well-being
Openalex Percentile: Top 81%
Muscle and Compartmental Disorders
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