A Retrospective Study of Pulmonary Function Tests in Bronchiectasis: An Infectious Disease of the Respiratory System

Introduction: Bronchiectasis, currently being recognized worldwide, is an abnormal dilatation of the bronchi and bronchioles brought on by recurrent cycles of inflammation and airway infection. Impaired pulmonary function has a predictive significance in bronchiectasis. When treating patients with suspected or confirmed respiratory diseases, pulmonary function tests (PFT) are useful examinations. Very few studies have been done on PFTs in bronchiectasis. The main aim of this study is to study PFTs in bronchiectasis. Method: This is a retrospective observational study done on 50 patients over two years at the tertiary care center. The previous records of patients were collected from the Pulmonary Function Lab. The spectrum of lung functions in patients with bronchiectasis was studied with the parameters in pulmonary function tests to see pre- and post-bronchodilator changes in the study population. Results: After post-bronchodilator use, flow volume curve parameters were significantly increased. The mean responses were significant for both FEV1 (increased from 1.29 to 1.53) and FEV1/FVC (increased from 70.9 to 78.4) criteria. However, there was no significant change for the mean MMEF 25/75 (increased from 1.09 to 1.45) criteria after bronchodilator use. The most common pattern was an obstructive defect 24 (48%). Conclusion: When diagnosing and treating bronchiectasis, lung function tests are a crucial evaluation tool. Objective information regarding the kind and severity of respiratory impairment is provided by lung function testing. An airflow obstruction is the most frequent ventilatory pattern associated with bronchiectasis. There is improvement in FEV1 and FVC following bronchodilator use in bronchiectasis.

Authors

Publication Details

Journal
The University of Louisville Journal of Respiratory Infections
Published
2025-05-15
DOI
https://doi.org/10.55504/2473-2869.1287
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Retrospective Study of Pulmonary Function Tests in Bronchiectasis: An Infectious Disease of the Respiratory System

Mahesh Shinde, Sangramsingh Dixit, D. B. Pardeshi, Akshat Dwivedi et al.
The University of Louisville Journal of Respiratory Infections
Respiratory viral infections research
article

A Retrospective Study of Pulmonary Function Tests in Bronchiectasis: An Infectious Disease of the Respiratory System

Mahesh Shinde, Sangramsingh Dixit, D. B. Pardeshi, Akshat Dwivedi, Avinas Rai, Kunal Shah, Kshitij Sarwey, Atharva Sharma, Yogeshwari Patil, Vinod Mutkule, Vidhi Kalwar, Vidya Bapmare, Sanket Jethlia
article en

Abstract

Introduction: Bronchiectasis, currently being recognized worldwide, is an abnormal dilatation of the bronchi and bronchioles brought on by recurrent cycles of inflammation and airway infection. Impaired pulmonary function has a predictive significance in bronchiectasis. When treating patients with suspected or confirmed respiratory diseases, pulmonary function tests (PFT) are useful examinations. Very few studies have been done on PFTs in bronchiectasis. The main aim of this study is to study PFTs in bronchiectasis. Method: This is a retrospective observational study done on 50 patients over two years at the tertiary care center. The previous records of patients were collected from the Pulmonary Function Lab. The spectrum of lung functions in patients with bronchiectasis was studied with the parameters in pulmonary function tests to see pre- and post-bronchodilator changes in the study population. Results: After post-bronchodilator use, flow volume curve parameters were significantly increased. The mean responses were significant for both FEV1 (increased from 1.29 to 1.53) and FEV1/FVC (increased from 70.9 to 78.4) criteria. However, there was no significant change for the mean MMEF 25/75 (increased from 1.09 to 1.45) criteria after bronchodilator use. The most common pattern was an obstructive defect 24 (48%). Conclusion: When diagnosing and treating bronchiectasis, lung function tests are a crucial evaluation tool. Objective information regarding the kind and severity of respiratory impairment is provided by lung function testing. An airflow obstruction is the most frequent ventilatory pattern associated with bronchiectasis. There is improvement in FEV1 and FVC following bronchodilator use in bronchiectasis.

The University of Louisville Journal of Respiratory InfectionsVol. 8(1)
Good health and well-being
Openalex Percentile: Top 84%
Respiratory viral infections research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.