A Deep-Learning Framework for Ovarian Cancer Subtype Classification Using Whole Slide Images
Ovarian cancer, a leading cause of cancer-related deaths among women, comprises distinct subtypes each requiring different treatment approaches. This paper presents a deep-learning framework for classifying ovarian cancer subtypes using Whole Slide Imaging (WSI). Our method contains three stages: image tiling, feature extraction, and multi-instance learning. Our approach is trained and validated on a public dataset from 80 distinct patients, achieving up to 89,8% accuracy with a notable improvement in computational efficiency. The results demonstrate the potential of our framework to augment diagnostic precision in clinical settings, offering a scalable solution for the accurate classification of ovarian cancer subtypes.
Authors
- Amir M. Hajiyavand (ORCID: https://orcid.org/0000-0002-6666-7866)
- Theodoros N. Arvanitis (ORCID: https://orcid.org/0000-0001-5473-135X)
- Ali Aflakian (ORCID: https://orcid.org/0000-0001-9777-7067)
- Qiufeng Yi (ORCID: https://orcid.org/0000-0002-5611-5769)
- Jiaqi Ye (ORCID: https://orcid.org/0000-0002-9593-8995)
- Karl D. Dearn (ORCID: https://orcid.org/0000-0002-8664-4303)
- Chenyang Wang (ORCID: https://orcid.org/0009-0004-1770-1011)
Institutions
- University of Birmingham (GB)
Publication Details
- Journal
- Studies in health technology and informatics
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3233/shti250606
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00