A Deep-Learning Framework for Ovarian Cancer Subtype Classification Using Whole Slide Images

Ovarian cancer, a leading cause of cancer-related deaths among women, comprises distinct subtypes each requiring different treatment approaches. This paper presents a deep-learning framework for classifying ovarian cancer subtypes using Whole Slide Imaging (WSI). Our method contains three stages: image tiling, feature extraction, and multi-instance learning. Our approach is trained and validated on a public dataset from 80 distinct patients, achieving up to 89,8% accuracy with a notable improvement in computational efficiency. The results demonstrate the potential of our framework to augment diagnostic precision in clinical settings, offering a scalable solution for the accurate classification of ovarian cancer subtypes.

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Publication Details

Journal
Studies in health technology and informatics
Published
2025-05-15
DOI
https://doi.org/10.3233/shti250606
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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A Deep-Learning Framework for Ovarian Cancer Subtype Classification Using Whole Slide Images

Amir M. Hajiyavand, Theodoros N. Arvanitis, Ali Aflakian, Qiufeng Yi et al.
Studies in health technology and informatics
Ovarian cancer diagnosis and treatment
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A Deep-Learning Framework for Ovarian Cancer Subtype Classification Using Whole Slide Images

Amir M. Hajiyavand, Theodoros N. Arvanitis, Ali Aflakian, Qiufeng Yi, Jiaqi Ye, Karl D. Dearn, Chenyang Wang
article en

Abstract

Ovarian cancer, a leading cause of cancer-related deaths among women, comprises distinct subtypes each requiring different treatment approaches. This paper presents a deep-learning framework for classifying ovarian cancer subtypes using Whole Slide Imaging (WSI). Our method contains three stages: image tiling, feature extraction, and multi-instance learning. Our approach is trained and validated on a public dataset from 80 distinct patients, achieving up to 89,8% accuracy with a notable improvement in computational efficiency. The results demonstrate the potential of our framework to augment diagnostic precision in clinical settings, offering a scalable solution for the accurate classification of ovarian cancer subtypes.

Studies in health technology and informaticsVol. 327
University of Birmingham (GB)
Good health and well-being
Openalex Percentile: Top 73%
Ovarian cancer diagnosis and treatment
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