Higher cortisol level and reduced circulating triiodothyronine in patients with cardiovascular diseases: A case-control study
This study found significant associations between elevated cortisol and reduced T3 levels in cardiovascular patients, particularly those with hypertension. Although stress-induced thyroid dysfunction remains a hypothesis, these findings suggest a potential link between cortisol, T3, and CVD. Further longitudinal research is needed to explore causal mechanisms.
Authors
- Syed Shakeel Raza Rizvi
- Muhammad Fiaz Khan
- Maleeha Akram
- Muhammad Arshad Javid (ORCID: https://orcid.org/0000-0002-5488-1283)
- Rodolfo Daniel Cervantes‐Villagrana (ORCID: https://orcid.org/0000-0002-6599-7994)
- Safir Ullah Khan (ORCID: https://orcid.org/0000-0002-1285-8907)
- Muhammad Rafi
Institutions
- Pir Mehr Ali Shah Arid Agriculture University (PK)
- Hazara University (PK)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
Publication Details
- Journal
- JRSM Cardiovascular Disease
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1177/20480040251340609
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Higher Education Commission, Pakistan