(Quantum) Fisher Information in Localization Microscopy
The precise localization of particles yields structural and dynamical information in applications ranging from fundamental physics to molecular biology. Here, we discuss how the concept of (Quantum) Fisher information can guide the development of localization techniques. Starting from dipole scattering, we discuss imaging based on elastic and inelastic (e.g. fluorescence) scattering and present experimental designs that increase the information obtained per detected photon.
Authors
- Thomas Juffmann (ORCID: https://orcid.org/0000-0002-7098-5736)
- Francisco Balzarotti (ORCID: https://orcid.org/0000-0003-1471-8120)
- Stefan Nimmrichter (ORCID: https://orcid.org/0000-0001-9566-3824)
- Jonathan Dong (ORCID: https://orcid.org/0000-0002-8315-5571)
Institutions
- University of Vienna (AT)
- Research Institute of Molecular Pathology (AT)
- University of Siegen (DE)
- Folkwang University of the Arts (DE)
- Max Perutz Labs (AT)
- Vienna Center for Quantum Science and Technology (AT)
- Vienna Biocenter (AT)
- École Polytechnique Fédérale de Lausanne (CH)
Publication Details
- Journal
- Photoniques
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1051/photon/202513158
- Citations
- 1
- Primary Topic
- Force Microscopy Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.25