Chain of Thought Strategy for Smaller LLMs for Medical Reasoning

This paper investigates the application of Chain of Thought (CoT) reasoning to enhance the performance of smaller language models in medical question-answering tasks. By leveraging CoT prompting strategies, we aim to improve model accuracy and interpretability, especially in resource-constrained settings. Using the PubMedQA dataset, we demonstrate how CoT helps smaller models break down complex medical queries into sequential steps, enabling more structured reasoning. While these models still face challenges in handling highly specialized medical content, CoT significantly improves their viability for healthcare applications. Our findings suggest that further optimization through methods like retrieval-augmented generation could further close the performance gap between smaller and larger models.

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Publication Details

Journal
Studies in health technology and informatics
Published
2025-05-15
DOI
https://doi.org/10.3233/shti250466
Citations
2
Primary Topic
Topic Modeling
Type
article
Field-Weighted Citation Impact
9.48
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article

Chain of Thought Strategy for Smaller LLMs for Medical Reasoning

Mowafa Househ, Hurmat Ali Shah
2 citations
Studies in health technology and informatics
Topic Modeling
9.48
article

Chain of Thought Strategy for Smaller LLMs for Medical Reasoning

Mowafa Househ, Hurmat Ali Shah
article en
2 citations

Abstract

This paper investigates the application of Chain of Thought (CoT) reasoning to enhance the performance of smaller language models in medical question-answering tasks. By leveraging CoT prompting strategies, we aim to improve model accuracy and interpretability, especially in resource-constrained settings. Using the PubMedQA dataset, we demonstrate how CoT helps smaller models break down complex medical queries into sequential steps, enabling more structured reasoning. While these models still face challenges in handling highly specialized medical content, CoT significantly improves their viability for healthcare applications. Our findings suggest that further optimization through methods like retrieval-augmented generation could further close the performance gap between smaller and larger models.

Studies in health technology and informaticsVol. 327
Hamad bin Khalifa University (QA)
Openalex Percentile: Top 3%
Topic Modeling
9.48
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