OMOP-on-FHIR: Integrating the Clinical Data Through FHIR Bundle to OMOP CDM

The harmonization of the OMOP Common Data Model (CDM) with HL7 FHIR aims to enhance interoperability in clinical research by harmonizing diverse healthcare datasets. This process, referred to as OMOP-on-FHIR, leverages FHIR Bundles for real-time clinical data exchange and transforms these resources into OMOP CDM format using an ETL process. The ETL pipeline, facilitated by tools like XSLT, enables the extraction, transformation, and loading of data while maintaining semantic consistency. By bridging these two standards, OMOP-on-FHIR promotes the seamless exchange of data across clinical systems and research-oriented databases, supporting global health studies, advanced analytics, and personalized medicine. This methodology advances cross-border research by providing a standardized approach to data management and analysis, thereby improving healthcare outcomes.

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Publication Details

Journal
Studies in health technology and informatics
Published
2025-05-15
DOI
https://doi.org/10.3233/shti250432
Citations
2
Primary Topic
Artificial Intelligence in Healthcare
Type
article
Field-Weighted Citation Impact
17.28
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article

OMOP-on-FHIR: Integrating the Clinical Data Through FHIR Bundle to OMOP CDM

Stefan Sauermann, Rada Hussein, Prabath Jayatissa, Lukas Rohatsch
2 citations
Studies in health technology and informatics
Artificial Intelligence in Healthcare
17.28
article

OMOP-on-FHIR: Integrating the Clinical Data Through FHIR Bundle to OMOP CDM

Stefan Sauermann, Rada Hussein, Prabath Jayatissa, Lukas Rohatsch
article en
2 citations

Abstract

The harmonization of the OMOP Common Data Model (CDM) with HL7 FHIR aims to enhance interoperability in clinical research by harmonizing diverse healthcare datasets. This process, referred to as OMOP-on-FHIR, leverages FHIR Bundles for real-time clinical data exchange and transforms these resources into OMOP CDM format using an ETL process. The ETL pipeline, facilitated by tools like XSLT, enables the extraction, transformation, and loading of data while maintaining semantic consistency. By bridging these two standards, OMOP-on-FHIR promotes the seamless exchange of data across clinical systems and research-oriented databases, supporting global health studies, advanced analytics, and personalized medicine. This methodology advances cross-border research by providing a standardized approach to data management and analysis, thereby improving healthcare outcomes.

Studies in health technology and informaticsVol. 327
University of Applied Sciences Technikum Wien (AT), Austrian Institute for Health Technology Assessment GmbH (AT)
Openalex Percentile: Top 1%
Artificial Intelligence in Healthcare
17.28
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OMOP-on-FHIR: Integrating the Clinical Data Through FHIR Bundle to OMOP CDM — Stefan Sauermann, Rada Hussein, et al. · Studies in health technology and informatics (2025) | TGRS Research Map | TGRS