Biological Properties of Jasminum Mesnyi Using Copper Nanoparticles

Abstract: The medicinal plant Jasminum mesnyi, or Japanese primrose jasmine, has a wide range of pharmacological effects, such as antibacterial, antioxidant, and anti-inflammatory effects. Discoveries of plant-based nanoparticles with enhanced biocompatibility and bioactivity have been made possible by recent developments in nanotechnology. In this work, we use a green synthesis method to create copper nanoparticles (CuNPs) from Jasminum mesnyi leaf extract. We next characterize and test these CuNPs in living organisms. The traditional technique of nanoparticle manufacturing often involves the use of harmful chemicals; however, this eco-friendly approach uses the phytochemicals found in Jasminum mesnyi as natural reducing and stabilizing agents. Several analytical techniques were used to characterize the synthesized CuNPs. These included transmission electron microscopy (TEM) for size and morphology determination, X-ray diffraction (XRD) for structural assessment, optical property analysis with ultraviolet-visible spectroscopy, functional group analysis with Fourier Transform Infrared Spectroscopy (FTIR), and more. The findings validated the production of stable, monodispersed CuNPs that exhibited ideal physicochemical characteristics that were well-suited for use in biomedicine. A battery of tests was used to determine the CuNPs' biological characteristics. Disc diffusion testing revealed significant inhibitory effects when applied to gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacterial strains. The antioxidant capacity was assessed using DPPH radical scavenging tests, which demonstrated a strong ability to neutralize free radicals. Also, using MTT assays, we looked at how the CuNPs affected certain human cancer cell lines, and we found that they selectively killed cancer cells while having very little impact on healthy cells.