Relationship of Alzheimer’s Disease and Related Dementias Plasma Biomarkers With Mobility in Cognitively Unimpaired Older Adults
These data suggest that p-tau181 and neurofilament light are potential markers of mobility performance in cognitively normal older adults, even when they are not associated with cognitive performance. Future studies should examine how such markers predict change over time in mobility and cognitive function and whether they may indicate pathways that could be targeted for preventive management.
Authors
- Suzanne Craft (ORCID: https://orcid.org/0000-0003-0591-8657)
- Xiaoyan Leng (ORCID: https://orcid.org/0000-0002-7610-7977)
- Atalie C. Thompson (ORCID: https://orcid.org/0000-0002-2817-6417)
- Paul J. Laurienti (ORCID: https://orcid.org/0000-0001-8871-9658)
- Thomas C. Register (ORCID: https://orcid.org/0000-0002-4078-0166)
- Stephen B. Kritchevsky (ORCID: https://orcid.org/0000-0003-3336-6781)
- Michelle M. Mielke (ORCID: https://orcid.org/0000-0001-7177-1185)
- Michael E. Miller
Institutions
- Wake Forest University (US)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-05-16
- DOI
- https://doi.org/10.1093/gerona/glaf110
- Citations
- 3
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Eli Lilly and Company
- Biogen
- Eisai
- Novo Nordisk