RECOVER study: a multicenter retrospective cohort study and comparison of the efficacy and safety of clazosentan and fasudil in patients with aneurysmal subarachnoid hemorrhage
Clazosentan outperformed fasudil in preventing cerebral vasospasm and improving overall outcomes in patients with aSAH. Despite initial concerns regarding fluid retention, appropriate perioperative management mitigated these risks, making clazosentan a superior treatment option across different patient groups.
Authors
- Basile Chrétien (ORCID: https://orcid.org/0000-0002-7483-2489)
- Shinji Shimato
- Takashi Yamanouchi (ORCID: https://orcid.org/0000-0001-6803-1901)
- Nobuhiko Mizutani
- Ikuya Takeuchi (ORCID: https://orcid.org/0009-0008-5620-1617)
- Ryuta Saito (ORCID: https://orcid.org/0000-0002-2484-1360)
- Masahiro Nishihori (ORCID: https://orcid.org/0000-0003-1645-0738)
- Toshinori Hasegawa (ORCID: https://orcid.org/0000-0001-6535-0229)
- Takashi Izumi (ORCID: https://orcid.org/0000-0003-2898-3371)
- Satoshi Maesawa (ORCID: https://orcid.org/0000-0001-7518-0171)
- Takeshi Okada (ORCID: https://orcid.org/0000-0003-2916-9398)
- Kiyo Nakabayashi
- Shigemasa Hayashi
- Kazuki Nishida (ORCID: https://orcid.org/0000-0003-0367-8557)
- Shinsuke Muraoka (ORCID: https://orcid.org/0000-0003-4225-110X)
- T Tsukada (ORCID: https://orcid.org/0000-0002-0332-2596)
- Ryotaro Sugita
- Takeshi Kinkori
- Shunsaku Goto (ORCID: https://orcid.org/0000-0003-3177-7691)
- Hideki Maki
- Shinji Shimato (ORCID: https://orcid.org/0000-0001-9424-8389)
- Осаму Сузукі (ORCID: https://orcid.org/0000-0002-2975-1452)
- Osamu Suzuki
- Shuntaro Takasu
- Masashige Iwasaki
- Takumi Asai
- T Kano
- Kazuki Ishii (ORCID: https://orcid.org/0009-0006-9581-6783)
- Hisashi Hatano
- Shigekazu Nakamura
Institutions
- Nagoya University Hospital (JP)
- Kariya Toyota General Hospital (JP)
- Okazaki City Hospital (JP)
- Nagoya Ekisaikai Hospital (JP)
- Handa City Hospital (JP)
- National Hospital Organization (JP)
- Nagoya Medical Center (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-05-16
- DOI
- https://doi.org/10.3171/2025.1.jns242509
- Citations
- 6
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 8.34