Primary Ovarian Malignant Melanoma: A Case Report

Primary ovarian melanoma (POM) is an exceedingly rare and aggressive form of melanoma that arises in the ovaries, distinct from metastatic ovarian melanoma, which is far more common. The rarity of this condition, coupled with its clinical similarities to other types of ovarian malignancies, makes it a challenging entity to diagnose and manage. We present the case of a 56-year-old woman who underwent a laparoscopically assisted vaginal hysterectomy and bilateral salpingo-oophorectomy due to pelvic organ prolapse and a left adnexal mass. The final histology showed a POM. She received adjuvant immunotherapy, and a year after the initial diagnosis, the patient remains alive and well, without any signs of recurrence or distant disease.