Fecal carriage of multidrug-resistant organisms increases the risk of hepatic encephalopathy in patients with cirrhosis: insights from gut microbiota and metabolite features
Fecal MDRO carriage was associated with endotoxemia, altered gut microbiota, metabolic changes, and a higher risk of HE. It's worthy to monitor fecal MDRO colonization in cirrhosis.
Authors
- Pei‐Chang Lee (ORCID: https://orcid.org/0000-0002-7492-2484)
- Kuei‐Chuan Lee (ORCID: https://orcid.org/0000-0003-4318-5511)
- Pei-Shan Wu (ORCID: https://orcid.org/0000-0002-2898-1475)
- Teh‐Ia Huo
- Chao‐Hsiung Lin (ORCID: https://orcid.org/0000-0001-6344-271X)
- Yi-Long Huang
- Chi‐Wei Huang (ORCID: https://orcid.org/0000-0002-2868-3961)
- Tien-En Chang
- Yi-Tsung Lin (ORCID: https://orcid.org/0009-0005-8434-6563)
- Ming‐Chih Hou
- Yun‐Cheng Hsieh
- Bernd Schnabl
Institutions
- National Yang Ming Chiao Tung University (TW)
- Taipei Veterans General Hospital (TW)
- University of California San Diego (US)
- Depomed (United States) (US)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-05-16
- DOI
- https://doi.org/10.1186/s13099-025-00706-3
- Citations
- 1
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Taipei Veterans General Hospital
- National Science and Technology Council
- San Diego Digestive Diseases Research Center, School of Medicine, University of California, San Diego