Haemodynamic response of normal aortic valves to stress using invasive, non-invasive, and computational techniques
Normal aortic valves demonstrated minimal pressure loss even during the high transvalvular flow generated by dobutamine infusion. Computational simulation using anatomy from a normal aortic valve behaved like a resistor, since mean gradient scaled directly with transvalvular flow.
Authors
- Pim A.L. Tonino (ORCID: https://orcid.org/0000-0002-2099-5426)
- D. T. Johnson (ORCID: https://orcid.org/0000-0003-4669-037X)
- Nils P. Johnson (ORCID: https://orcid.org/0000-0002-0897-2301)
- Vijay Govindarajan (ORCID: https://orcid.org/0000-0001-6046-5262)
- Fabienne E. Vervaat (ORCID: https://orcid.org/0000-0001-6693-7355)
- Mohamed El Farissi (ORCID: https://orcid.org/0000-0002-0637-0796)
- Jesse P. A. Demandt (ORCID: https://orcid.org/0000-0001-6506-7108)
- Richard L. Kirkeeide (ORCID: https://orcid.org/0000-0002-0438-6639)
- Rob Eerdekens (ORCID: https://orcid.org/0000-0003-3585-0999)
Institutions
- Boston Children's Hospital (US)
- Memorial Hermann (US)
- Radboud University Nijmegen (NL)
- Catharina Ziekenhuis (NL)
- Eindhoven University of Technology (NL)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- European Heart Journal - Imaging Methods and Practice
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/ehjimp/qyaf061
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- ZonMw