Chemotherapy-related adverse drug reaction and associated factors among adult cancer patient attending Jimma medical center oncology unit, Southwest Ethiopia

We can deduce from the data that adverse drug reactions are a significant concern for patients undergoing chemotherapy, with nearly two-thirds experiencing ADRs. The most common reactions are nausea and vomiting, which are mostly mild and probable. Age, gender, and the use of several chemotherapy drugs were associated with an increased risk of adverse drug reactions. Hence all concerned bodies should make an effort for early detection and take preventive measure of chemotherapy-related adverse drug reactions. Where feasible, use chemotherapy protocols with alower risk of ADRs. Evaluate dose adjustments for elderly patients. Implement protocols for risk assessment before initiating chemotherapy.

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Journal
PLoS ONE
Published
2025-05-16
DOI
https://doi.org/10.1371/journal.pone.0321785
Citations
4
Primary Topic
Pharmaceutical Practices and Patient Outcomes
Type
article
Field-Weighted Citation Impact
4.90
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article

Chemotherapy-related adverse drug reaction and associated factors among adult cancer patient attending Jimma medical center oncology unit, Southwest Ethiopia

Mubarik Fetu Semman, Biruk Tafese Moges, Aster Wakjira Garedo, Mukerem Sultan Shrmeka et al.
4 citations
PLoS ONE
Pharmaceutical Practices and Patient Outcomes
4.90
article

Chemotherapy-related adverse drug reaction and associated factors among adult cancer patient attending Jimma medical center oncology unit, Southwest Ethiopia

Mubarik Fetu Semman, Biruk Tafese Moges, Aster Wakjira Garedo, Mukerem Sultan Shrmeka, Feki Nekir Dereja
article en
4 citations

Abstract

We can deduce from the data that adverse drug reactions are a significant concern for patients undergoing chemotherapy, with nearly two-thirds experiencing ADRs. The most common reactions are nausea and vomiting, which are mostly mild and probable. Age, gender, and the use of several chemotherapy drugs were associated with an increased risk of adverse drug reactions. Hence all concerned bodies should make an effort for early detection and take preventive measure of chemotherapy-related adverse drug reactions. Where feasible, use chemotherapy protocols with alower risk of ADRs. Evaluate dose adjustments for elderly patients. Implement protocols for risk assessment before initiating chemotherapy.

PLoS ONEVol. 20(5)
Jimma University (ET), Wolkite University (ET)
Good health and well-being
Openalex Percentile: Top 5%
Pharmaceutical Practices and Patient Outcomes
4.90
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