Chemotherapy-related adverse drug reaction and associated factors among adult cancer patient attending Jimma medical center oncology unit, Southwest Ethiopia
We can deduce from the data that adverse drug reactions are a significant concern for patients undergoing chemotherapy, with nearly two-thirds experiencing ADRs. The most common reactions are nausea and vomiting, which are mostly mild and probable. Age, gender, and the use of several chemotherapy drugs were associated with an increased risk of adverse drug reactions. Hence all concerned bodies should make an effort for early detection and take preventive measure of chemotherapy-related adverse drug reactions. Where feasible, use chemotherapy protocols with alower risk of ADRs. Evaluate dose adjustments for elderly patients. Implement protocols for risk assessment before initiating chemotherapy.
Authors
- Mubarik Fetu Semman (ORCID: https://orcid.org/0000-0001-7921-0243)
- Biruk Tafese Moges
- Aster Wakjira Garedo
- Mukerem Sultan Shrmeka
- Feki Nekir Dereja
Institutions
- Jimma University (ET)
- Wolkite University (ET)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-16
- DOI
- https://doi.org/10.1371/journal.pone.0321785
- Citations
- 4
- Primary Topic
- Pharmaceutical Practices and Patient Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.90