Experience of Managing a Child with Bruton's Disease

National Center for Maternity and Childhood Care, Bishkek, Kyrgyzstan Abstract. Objective of the work. To update information on hereditary agammaglobulinemia in the Kyrgyz Republic, to describe a case of Bruton's disease in a boy I.A., 9 years old. The boy has been under our supervision since October 2024. The child is from the third pregnancy, delivery on time. He was breastfed until 2 years old. At the age of 1 year, he suffered from bilateral purulent otitis. At 1.5 years, a shunting operation of the tympanic cavity was performed. Bilateral sensorineural hearing loss was diagnosed when he was 2 years old. At 2.5 years old, he underwent cochlear implantation surgery. Since birth, he has often suffered from acute respiratory diseases, often with purulent complications. Based on the collected data (anamnesis, clinical picture, laboratory and instrumental and genetic studies), the child was diagnosed with Bruno's disease (X-linked agammaglobulinemia).